Weber-Christian disease is an inflammatory disease of subcutaneous fat tissue which is clinically characterized by relapsing, febrile, nodular, nonsuppurative panniculitis. The cause is unknown, but the disease has been attributed to an
autoimmune
reaction, infections, halogen compounds, sarcoidosis, SLE and a1-antitrypsin deficiency.
We report here in a case of Weber-Christian disease in a 8-year-old girl, who had indurated erythematous subcutaneous nodules on the extremities, buttock and trunk accompanied by various general symptoms such as fever, malaise, arthralgia and
edema
of
the abdomen and legs. This case was successfully treated with dapsone. (Kor J Dermatol 1993 ; 31(1) : 109-113)
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